Insomnia (Off-Label): At lower doses like 50 mg, trazodone acts heavily on histamine and alpha-adrenergic receptors to induce sedation. It helps people fall asleep faster and stay asleep longer without the high risk of dependence associated with traditional sleeping pills.
Depression & Anxiety: While the standard starting dose for depression is typically higher (usually 100 mg to 150 mg daily), doctors may start patients at 50 mg to minimize initial side effects or use it to treat depression accompanied by severe anxiety or sleep disturbances.




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